The treatment is generally safe. Redness, swelling, or bruising usually disappears within a few days.

What is a cosmetic polynucleotide treatment?

Q: Is the treatment painful?

The injections may be slightly sensitive, but a numbing cream is usually applied to make the procedure comfortable.

Q: How long do the results last?

The effects usually last 6 to 12 months, depending on your skin type and lifestyle.

Q: What does a treatment cost?

The costs vary per clinic, but are often between AED 1100 and AED 1300 per session.

A treatment with polynucleotides, sometimes also known as salmon sperm, skin booster DNA injections, or bio-revitalisation with polynucleotides, is a new way to naturally improve and rejuvenate the skin. The goal of this treatment is to restore skin quality, reduce signs of ageing, and give a fresh, healthy appearance.

What are polynucleotides?

Polynucleotides are natural building blocks of DNA and RNA that naturally occur in our bodies. In cosmetic treatments, they are used to hydrate and firm the skin, while stimulating the natural healing and renewal of skin cells. The polynucleotides used in these treatments are completely safe and are broken down by the body.

What does a polynucleotide treatment involve?

A polynucleotide treatment, also known as a salmon filler, is an innovative injectable or skin booster therapy that restores and rejuvenates the skin from within. Polynucleotides are biological molecules derived from salmon DNA, specifically from salmon sperm.

Read more:
What is PhilArt?

How does a polynucleotide treatment work?

During the treatment, polynucleotides are injected into the skin with fine needles. A polynucleotide treatment, sometimes called salmon sperm, is an innovative injectable or skin booster that restores and rejuvenates the skin from within.

Polynucleotides are biological molecules derived from salmon DNA (salmon sperm). The doctor focuses on areas where the skin needs extra support, such as the face, neck, hands, or décolleté.

Treatments around the eyes, for example for dark circles or fine lines, are among the popular PDRN treatments. Usually, 3 to 4 sessions are needed, spaced 2 to 4 weeks apart. Each session lasts about 30 minutes.

What is a PDRN treatment?

Polynucleotides is a complicated word. Many clinics describe this treatment as PN injections, PDRN treatment, biorevitalisers, or nucleotide treatment.

For which skin concerns is this treatment suitable?

This treatment is suitable for:

Reducing fine lines and wrinkles
Addressing sagging or dull skin
Repairing damaged skin, for example due to sun exposure
Improving skin texture and tone
Hydrating dry or dehydrated skin

The treatment is often recommended for people looking for a natural way to improve their skin without undergoing surgery.

What can you expect from ‘PDRN’?

Softer and fuller skin
Fewer fine lines and wrinkles
A healthy and radiant appearance

Some results are visible after the first treatment, but the full effect usually becomes noticeable after a few weeks.

Is polynucleotide safe?

A treatment with polynucleotides is considered safe for several reasons:

Use of natural substances: Polynucleotides are compounds that naturally occur in the body. They support skin cell repair without chemical or synthetic additives.
Biocompatibility: Polynucleotides are well tolerated by the body and carry a low risk of allergic reactions or rejection.
Clinical studies: Research supports the effectiveness and safety of polynucleotides in skin improvement. Side effects are usually mild and short-lived, such as redness, swelling, or bruising.
Treatment by specialists: The procedure is carried out by qualified professionals, which further increases safety.
Minimal invasiveness: The treatments do not require surgery and involve a short recovery time, lowering risks compared to invasive procedures.

If you are considering this treatment, discuss your options with a qualified specialist to ensure the right approach for your skin type and needs.

Advantages and disadvantages of a polynucleotide treatment

Advantages:

Natural skin improvement without surgery
Suitable for almost all skin types
Promotes deep hydration and skin repair

Disadvantages:

Multiple sessions needed for optimal results
Temporary swelling or redness after the treatment
Not suitable during pregnancy or for certain medical conditions

Reviews

I had a fantastic experience at Biolite Clinic. I initially came in thinking I needed to start Botox, but after a thorough consultation with Dr. Ola, she actually advised me against it — for the time being at least. That, to me, is the mark of a truly honest and skilled doctor.

I did the Diamond Glow facial, Microneedling, and Polynucleotides treatment — and I’m genuinely so happy with the results! From start to finish, I felt incredibly well cared for. A big thank you to Brenda and Melanie, who were not only professional but also so attentive and kind throughout the entire process. Show less »

Creol

Biolite Clinic Dubai

4 July 2025 09:09

FAQ

Is the treatment painful?

How long do the results last?

Are there any risks?

What does a treatment cost?

Which clinics in the United Arab Emirates offer this treatment?

On Injectablesbooking, you can easily find clinics that offer this treatment. The platform provides an overview of recognised clinics and DHA-licensed doctors. Compare clinics based on experience, prices, and reviews to make the best choice.